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Zyban/Wellbutrin

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Though I haven't actually tried it, I do hear great things about Zyban, brand name: Wellbutrin. Originally prescribed for depression, smokers who took Wellbutrin started noticing that they have fewer nicotine cravings and less intense withdrawal symptoms. And the cool thing about Wellbutrin is that, even if you don't have depression, Wellbutrin still works on nicotine cravings (and it doesn't alter your mood if you're not depressed). Why? Because, as chance would have it, people who are depressed and people who quit smoking have many of the same side effects, including irritability, fatigue, anxiety, and shifting energy levels. So, the drug works on those symptoms, making it easier to cope with nicotine withdrawal.

Studies have actually shown that 25-35 people who use Zyban or nicotine replacement therapy actually stay smoke-free for six months; compare that to the 10 percent of successful quitters who go cold turkey. And many professionals suggest that Zyban, in combination with NRTs, is probably your best bet for remaining smoke free. The nag about Wellbutrin, however, is that - like the nicotine spray and the nicotine inhaler -- you need a doctor's prescription.

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